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Glutathione Levels in Human Tumors

The animals were fed standard chow for 1 week in a suitable experimental environment with a 12-h/12-h light/dark cycle and a controlled temperature (25C 1C) and humidity (50 10%)

To maintain the intracellular redox balance, GSH is replenished through the reduction of GSSG by glutathione reductase enzyme

We explore the half-life of glutathione, the regulation of glutathione synthesis, and its sensitivity to fluctuations in amino acid input

By addressing underlying metabolic dysregulation, reducing liver fat, and alleviating inflammation, tirzepatide shows potential in enhancing liver function and slowing the progression of NAFLD