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GLP-1 receptor agonists, such as GLP-1 and GLP-2, work differently but complement TRT by: Reducing Appetite: GLP-1s slow gastric emptying and signal satiety to the brain, helping men control food intake

Some people who started taking GLP-1 agonists to treat obesity or diabetes have also reported improved fertility

By facilitating the transport of fatty acids into the mitochondria, it enables efficient conversion of fats into usable energy, supporting both physical and mental performance

Competing interests: All authors have completed the ICMJE uniform disclosure form at www.icmje.org/disclosure-of-interest/ and declare the following: support from Brigham and Womens Hospital, Harvard Medical School, the Netherlands Organization for Scientific Research, Patient-Centered Outcomes Research Institute, Food and Drug Administration, National Institutes of Health, National Institute on Aging, American Diabetes Association for the submitted work

Thats become common because GLP-1 drugs are expensive for health plans and the employers that pay for them