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266-268 A Mediterranean diet in particular has been shown to lower risks of diseases common in postmenopausal women, such as cardiovascular disease, overweight and obesity, type 2 diabetes, and breast cancer, and may also slow bone loss and cognitive decline while supporting healthy mood

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In the vascular system, oxidative stress in diabetes activates ROS-mediated Akt and extracellular signal-regulated kinase 1/2 (ERK1/2) signaling cascades, promoting autophagy in endothelial cells while downregulating HDAC6 expression, which impairs cell migration and adhesion