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Hamilton, E
Semaglutide, a GLP-1 receptor agonist, mimics the action of the hormone GLP-1 to regulate blood sugar levels and promote weight loss
Such a direct GLP-1 mechanism is supported by studies using native GLP-1 and exenatide in healthy people and patients with T2DM showing that the acute increase of HR was not preceded by a decrease in blood pressure, was not associated with changes in plasma levels of adrenaline or noradrenaline, and was independent of GLP-1 glucoregulatory effects [11, 34, 35]
It may help stabilize mood and reduce emotional eating or stress-related cravings by improving neurotransmitter balance
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