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Thus, the most promising quantitative approaches are those that rely on trapping the reactive sulfur atom(s) in a diagnostic product and then quantifying these, typically by mass spectrometry (MS) 28,31,32,33

and into the roles that melanocytes and melanin play in the maintenance of homeostasis of the oral mucosa, as well as into the roles physiological or benign oral mucosal melanin hyperpigmentations may play as precursors of premalignant and malignant oral melanotic lesions

The different effect on the hydration status seen in our groups might have been caused by the different baseline hydration status as fluid retention tends to progress with renal impairment 34

Studies have demonstrated that both discontinuation and submaximal doses of RAASi are associated with an elevated risk of cardiorenal morbidity and mortality [6]