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A landmark paper in 2021 describes patients taking 2.4mg (the maximum dose of Wegovy) for 68 weeks, and yielding sustained, clinically relevant weight loss of up to 15%
That's lower than the 7.1% discontinuation rate seen with semaglutide 2.4 mg in the STEP trials, suggesting tirzepatide is better tolerated at maximum doses despite the higher absolute milligram amount
What does progesterone do in perimenopause and menopause
Recommend having it professionally done if its your first time to try it out
The exact mechanism connecting these protein changes to reduced alcohol intake requires more investigation
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