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Currently, research vendors operate in a gray area where demand exists but no legal pharmaceutical alternative is available

Heres what makes it stand out: Smaller doses help reduce side effects, so treatment feels more comfortable from the beginning

But that has changed

In 2018, FDA published guidance to 503A pharmacies on what will be considered unauthorized compounding of a product that is essentially a copy of an FDA-approved product, with an exception available when the prescriber documents on the prescription that the compounded drug product produces a significant difference for the identified individual patient. Under the 2018 guidance, FDA generally does not intend to question prescriber determinations that are documented in a prescription or notation. To date, patient-specific GLP-1 compounding activities have often included adding supplemental ingredients to combat side effects of the GLP-1 products or customizing doses, with a significant percentage of prescriptions for customization written by telehealth prescribers

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