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GPx3 As mentioned above, elevated levels of ROS play a crucial role in the progression of breast cancer [99]
471 Knocking down FTH in cardiomyocytes prevents free iron from being stored in ferritin, increases unstable iron pools, promotes intracellular ROS production, activates oxidative stress, and causes ferroptosis in cardiomyocytes, leading to age-related heart damage
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GI side effects may worsen, and clearance is unknown
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