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Begin gradually, particularly when incorporating a new treatment such as retatrutide

But the math shows why time-limited coverage is appealing to payers that struggle to pay for beneficiaries' GLP-1 prescriptions, said Michelle Gourdine, chief medical officer for the pharmacy benefit manager CVS Caremark

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In a phase 2 trial, individuals on retatrutide experienced decreases in overall body fat of up to 26.1%

[PMID: 32547687] PubMed record related to this compound for laboratory literature review