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Chronically high glucose fuels a flood of free radicals, and over time patients are left with less of the reduced, protective form of GSH and more of the oxidized, exhausted kind a red flag of cellular stress
Simultaneously, NAD+ levels increased by 1.2 to 1.6 fold compared to untreated cells
A decent pair of binoculars can also show them as tiny points of light lined up on one or both sides of the planet, though a telescope will show them more clearly
10.1182/hematology.2021000307 30 HanJ.SarafS
Furthermore, IL-1, TNF-, and complement component subunit 1q (C1q) encourage the transformation of astrocytes into reactive astrocytes (A1), subsequently impairing the astrocytic capacity to regulate microglial activity [132]
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