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IGF-1 LR3 is a long-acting analog of human IGF-1

The hypothalamus controls the pituitary by producing two categories of hormones: Releasing hormones (e.g., TRH, GHRH, CRH, GnRH) travel to the anterior pituitary and stimulate it to secrete specific hormones Inhibiting hormones (e.g., somatostatin, prolactin-inhibiting factor) prevent the anterior pituitary from secreting specific hormones, keeping levels in check The pituitary gland has two structurally and functionally distinct lobes: The anterior lobe (adenohypophysis) manufactures and secretes six major hormones: GH, TSH, ACTH, FSH, LH, and PRL

1, 2009, pp