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10.1016/j.jhep.2017.10.006 18

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In support of the role of Mc2r in pigmentation, KEGG analysis revealed enrichment of the tyrosine metabolism pathway (dre00350), which includes key melanin biosynthesis genes

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It is a big indication (5% of western population) and growing rapidly

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With the following signs, however, you should arrange a prompt assessment: Patchy, round hair loss (bald spots larger than 1 cm): suggests alopecia areata rather than telogen effluvium

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Increase baseline fluid intake by 20% and add an electrolyte supplement

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