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Who Should Consider GLP-1 Medications
Strong preclinical coverage: improved insulin sensitivity in aged and high-fat-fed mice (Lee et al., Cell Metabolism 2015) and roughly doubled treadmill running time in old mice (Reynolds et al., Nature Communications 2021)
Semaglutide can reduce appetite, so consistent meals with enough protein help protect lean muscle
GLP-1 medicines and the treatment of obesity GLP-1RAs led to weight loss investigations, with liraglutide 3 mg daily approved for weight loss in 2014, followed by semaglutide 2.4 mg weekly in 2021, and tirzepatide in 2023
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