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& Fleseriu, M
For Alzheimers disease, researchers gave 204 participants with mild to moderate disease liraglutide (a GLP-1 that pre-dated Ozempic) and measured how much brain volume they lost
This trend highlights a gap between evidence-based medicine and everyday practice
The triple-receptor action (GLP-1, GIP, glucagon) is the reason it outperforms semaglutide and tirzepatide
That makes native IGF-I awkward as an experimental tool, because in any system containing serum or secreted IGFBPs the concentration a researcher adds is not the concentration the receptor sees
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