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The peptide upregulates expression of various angiogenic factors and promotes formation of new capillary networks, which are essential for adequate tissue perfusion and nutrient delivery during healing processes

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Increased levels of adiponectin in non-human primates and humans with metabolic disease (type 2 diabetes, obesity and NASH) have been consistently observed following treatment with various FGF21 analogs (183, 244246)

Barnham, K