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This Research Topic is part of a series with: The changing faces of glutathione, a cellular protagonist., Volume II Glutathione (GSH) has been described for a long time just as a defensive reagent against the action of toxic xenobiotics (drugs, pollutants, carcinogens), both directly and as a cofactor for GSH transferases
Identity of synthetic AQ-QI and DEAQ-QI was verified by mass spectrometry and the purities were above 95% (Supplementary Figure S1), as determined by HPLC-UV and LC-TOF-MS ( Cell Culture HepG2 cells were cultured in collagen-coated plates and maintained in DMEM containing 10% FBS, 1% penicillin/streptomycin (PAA Laboratories, Austria), 1% ultraglutamine (Lonza, Switzerland) and 1% non-essential amino acids (Sigma-Aldrich, Germany)
This depends on dose and vial size: 2mg vial at 200mcg/dose = 10 doses 2mg vial at 300mcg/dose = 6.6 doses (approximately 6) 5mg vial at 200mcg/dose = 25 doses 5mg vial at 300mcg/dose = 16.6 doses (approximately 16) At a standard protocol of 200-300mcg once or twice daily, a 5mg vial lasts 8-25 days depending on frequency and dose
PubMed Nass R, Pezzoli SS, Oliveri MC, et al
Kojic: Empche la formation Mlanine, conditions peau que les taches de rousseur et les taches disparaissent peu peu, rvlant une peau plus claire
