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Important safety considerations include risks of medullary thyroid carcinoma (contraindicated in patients with MEN2 or family history of MTC), pancreatitis, gallbladder disease, acute kidney injury with severe gastrointestinal adverse effects, and potential diabetic retinopathy complications in patients with type 2 diabetes
And while not as prominent in the weight-loss space, Pfizer (NYSE: PFE) has recently doubled down on its efforts in that industry, signing a $2.1 billion licensing agreement in December 2025 with a Chinese pharmaceutical company to develop its early-stage weight-loss pill
But people with type 1 diabetes or type 2 diabetes can also develop this condition
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