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2014;2:e429
Several factors contribute to the expression and regulation of DPP-4 in the body
But insulin also slows down how fast the gut moves, which means people have bowel movements less often
So that confirms the idea of Minkowski that this is a pancreatic deficiency disease
This is particularly concerning given that people with obesity-related comorbidities may reap the greatest benefit from treatment. Thomsen noted the irony that patients most likely to benefit from sustained treatment were often those most likely to abandon it due to side effects or other health complications
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