Severe abdominal pain, particularly if localized to the upper abdomen and radiating to the back, may indicate pancreatitisa rare but serious adverse effect of GLP-1 agonists that requires emergency evaluation
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Some researchers prefer this because the slightly lower concentration gives them more precision, especially if they are doing half-step escalations like 6mg or 10mg between the standard protocol doses
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In other words GLP-1s and there are a range of these treatments all have an effect which is predominantly around high sugars and if the sugar becomes low, the effect is switched off, and it is the reason we see very low rates of low blood sugars so called 'hypos', or hypoglycemic episodes that occur with GLP1 treatments