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Third, the matching methods adopted in this study mimicked a randomized controlled trial, which provides a higher level of evidence

FDA News Release

Biochem Biophys Res Commun 231:793796

The estimated treatment difference for tirzepatide versus insulin degludec ranged from -0.59% to -1.04%, with all tirzepatide doses demonstrating statistical significance

Abstract Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) represent a major advancement in obesity treatment, offering robust efficacy in weight loss and metabolic regulation