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Carnitine deficiency is observed in disorders of the mitochondrial respiratory chain, such as cytochrome c oxidase deficiency, in which the ATP depletion may compromise the energy-dependent carnitine uptake

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( Effector proteins We used the glutathione-S-transferase-effector protein chimera p21-activated kinase protein binding domain, a Rac1 effector protein purchased from Millipore Sigma

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