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Dose Is the Lever That Controls Most Side Effects DAC dosing and side-effect incidence: 0.5 mg per injection: very few reports of anything 1 mg per injection (1 to 2 mg weekly): the standard range, mild side effects in some users 2 mg+ per injection: water retention and tingling reports climb noticeably No-DAC dosing and side-effect incidence: 100 mcg per injection: essentially side-effect-free for most users 200 to 300 mcg per injection: occasional mild headache 500 mcg+ per injection: more headache and flushing reports My honest take: most side-effect complaints I see come from people who jumped to the top of the dose range in week one