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However, gastrointestinal side effects were more common among orforglipron users, highlighting the need for further research to ensure its safety and effectiveness in patients with severe gastrointestinal disease and issues related to the gastrointestinal tract

This product has not been evaluated by the FDA for safety or effectiveness

SOURCE: U.S

A Potential New Osteoarthritis Therapeutic Class Together, these findings suggest that GLP-1 receptor modulation influences multiple joint-specific pathways: reducing inflammation, preventing cartilage catabolism, promoting matrix regeneration, and modifying synovial tissue responses

These medications are FDA-approved for adults with obesity or weight-related health risks