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transient impairment of glucose tolerance is possible, particularly in individuals with pre-existing insulin resistance Injection site reactions: Mild and typically localised Contraindications include active malignancy (GH-IGF-1 signalling can promote tumour growth), pituitary-dependent conditions, pregnancy, and active diabetic retinopathy

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It is worth noting that we streamlined our discussion and introduced additional approaches to comprehensively address our findings and suggest potential areas for future research

Its stability in acidic media makes it a practical subject for both oral and parenteral animal study designs, and for in-vitro work where pH tolerance simplifies handling

Furthermore, GLP-1 RAs have shown promise in reducing blood pressure, a crucial benefit given that high blood pressure can exacerbate both kidney and heart problems in diabetes