They remain prescription therapeutics that should be physician-managed and pharmacy-sourced
Combined with Vitamin B12: This essential vitamin helps support healthy energy levels, red blood cell production, and overall metabolism, while also contributing to mood and focus
A qualitative sub-study of the trial by Whicher and colleagues 144 over 17 patients with overweight or obesity and schizophrenia-spectrum disorders found that most of the interviewees and their clinicians had had positive experiences regarding GLP-1RA administrations

While GLP-1 weight loss medication can be incredibly effective, there are important GLP-1 contraindications to consider: Medical Exclusions Absolute contraindications include: Personal or family history of medullary thyroid carcinoma (a type of thyroid cancer) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Severe gastroparesis (delayed stomach emptying) History of pancreatitis (though this is sometimes relative depending on the cause) Situations Requiring Caution Your healthcare provider will carefully evaluate if you have: Kidney disease or reduced kidney function Gallbladder disease or history of gallstones History of depression or eating disorders Pregnancy or breastfeeding (these medications are not recommended during pregnancy) Diabetic retinopathy (may worsen initially with rapid blood sugar improvements) Potential Side Effects to Consider Common side effects that might affect GLP-1 candidacy include: Nausea and vomiting (especially when starting) Diarrhea or constipation Decreased appetite (which is therapeutic but can be concerning if extreme) Fatigue during the adjustment period Most people find these effects manageable, and they often improve over time, but it's important to discuss your tolerance for potential side effects with your provider

Clinical trials show variable lipid effects across GLP-1 receptor agonists, with differences generally modest and correlating with weight loss achieved