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doi: 10.1093/ajcn/nqx025, 22
In a country where one in three adults has a BMI higher than 25, and also has access to cheaper semaglutides after its patent expired on March 20, the drug packs both relief and caution for misuse
However, retatrutide may have superior benefits for insulin resistance and glycemic regulation , due to: Enhanced insulin sensitivity from GIP agonism Reduced hepatic glucose output from glucagon signaling modulation Improved beta-cell function Clinical Insight: Retatrutide reduced fasting glucose and A1C levels with similar or better efficacy than tirzepatide in early trials
