going from tirzepatide to semaglutide vs Tirzepatide: Key Differences Semaglutide GLP-1 Vs Zepbound For

doi: 10.3390/ijms232012403 51

Sigma) supplemented with 10% fetal calf serum (PAN Biotech) and 100U of penicillin/100 g of streptomycin per ml (PAN Biotech) in a 5% CO 2 atmosphere at 37C

Common side effects can include: Nausea Vomiting Diarrhea Constipation Decreased appetite Abdominal pain Severe or long-term side effects can include: Gastroparesis (paralyzed stomach): Can lead to chronic vomiting, malnutrition, and dependence on feeding tubes

However, recent research has raised questions about whether some GLP-1 medications, especially semaglutide, may be associated with a higher risk of a rare but serious eye condition called NAION

Similarly, as seen in non-syndromic obesity (43, 44), semaglutide treatment discontinuation, which occurred in Patient 1 and Patient 2, resulted in weight regain