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oxidized cardiolipin not only triggers NLRP3 but also signals for mitophagy (mitochondrial autophagy) as a quality control
Maggio AB, Belli DC, Puigdefabregas JWB, Rizzoli R, Farpour-Lambert NJ, Beghetti M, et al
It occurs naturally in cells and is a cofactor in dozens of enzymatic reactions involved in detoxification.* As an antioxidant, glutathione directly quenches several reactive oxygen species (free radicals).* The bodys benefits from maintaining a normal level of glutathione include support for liver function, pulmonary function, immune function, bowel health, carbohydrate metabolism, cardiovascular health, cognitive health, and eye health.* Glutathione-SR is a breakthrough in glutathione supplementation because its sustained-release formula protects it from stomach acid and digestive enzymes, allowing for a slower release and a more steady level in the bloodstream of this essential nutrient.* Glutathione is the most abundant anti-oxidant
For those with more advanced OA, the researchers are working to develop a regenerative hydrogel" to fill the cartilage gaps
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