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Although there is limited direct evidence for this species having functional effects on host metabolic profile, studies in DIO mice have demonstrated reduced adiposity and improved glucose tolerance following oral administration of Akkermansia muciniphila 71,72
1 This insulin secretion causes an overall decrease in blood sugar levels, reduces the production of glucagon, which prevents the release of glucose storage from the liver, and induces a satiety response that elevates insulin sensitivity and causes weight loss
Gao Y-M, Feng S-T, Wen Y, Tang T-T, Wang B, Liu B-C
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Abd El Aziz MS, Kahle M, Meier JJ, Nauck MA
