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After transforming treatment of type 2 diabetes and obesity, semaglutide and other GLP-1 medicines have been approved for other conditions including MASH (metabolic dysfunction-associated steatohepatitis)
These evidences highlighted once more the divergent role of the two coactivators in the liver, with PGC-1 being more involved in catabolic pathways and PGC-1 inducing anabolic processes, such as the synthesis of new fatty acids
But for patients experiencing sustained fatigue during the rapid weight loss phase of tirzepatide therapy
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