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Sudden discontinuation can lead to rapid weight regain and potential metabolic disturbances, which can undermine the progress made during treatment

10.1186/s12974-019-1434-3 67 MaY.ZhangY.JiangH.XiangS.ZhaoY.XiaoM.et al (2021)

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Direct actions of GLP-1 analogues on AMP-activated protein kinase activity are distinct from cyclic AMP accumulation