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GLP-1 and GIP receptors can form dimers, which then increases the amount of cAMP produced and, furthermore, can change the second messenger cascade to a PLC-IP3-PiP3-Alt/PKB cascade [103, 104] (Fig

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In contrast, pharmacologic strategy in older adults must balance efficacy with safety: slower-acting agents such as liraglutide, or gut-restricted compounds like orlistat, may be preferred to avoid excessive weight loss, sarcopenia, or nutritional deficiencies

Discussion The present study demonstrated that the Hultman et al

Abnormally elevated blood sugar levels have been tracked as long as 10 years before a formal diagnosis of diabetes is confirmed