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Accumulation of cytosolic succinate results the inhibition of the 2-oxoglutarate and Fe 2+ -dependent dioxygenases [prolyl hydroxylase domain (PDH) enzymes] responsible for the hydroxylation of the -subunit (HIF-1) of HIF-1
Tabernero J, Hozak RR, Yoshino T, Cohn AL, Obermannova R, Bodoky G, et al
UAE Lab Research GLP-3 is an investigational multi-receptor agonist (GLP-1, GIP, and glucagon receptor)
Pesticide contamination of our food, soil, air, and water
Data are presented as the mean SD of three or four biological replicates in three or four independent samples
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