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Needle gauge matters
Similar acute haemolytic attacks have been observed, predominantly in men of Afro-Caribbean origin, in response to primaquine and a variety of other drugs, including dapsone, the antipyretic acetylphenylhydrazine, the antibacterial bactrim/septrim, sulphonamides and sulphones, whose only common feature is that they all undergo cyclic non-enzymic reactions in the presence of oxygen to produce hydrogen peroxide and a variety of oxygen radicals that can cause oxidative damage to membrane lipids, leading to haemolysis
Tannins as an alternative to antibiotics
Verhulst ML, van Oijen AH, Roelofs HM, Peters WH, Jansen JB
This also causes a loss of cells that produce intrinsic factor and secrete hydrochloric acid
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