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Symptoms of vitamin D deficiency include fatigue, poor sleep, muscle weakness, pain, stress, anxiety, and depression

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Estradiol (E 2 ) and BDNF have also been shown to help regulate many of the same biological functions, including modulating the activity of NMDARs (especially the NR 2B subunit), promoting neurogenesis in the dentate gyrus, and facilitating the formation of memories [276, 277]

The copper ion in GHK-Cu participates in superoxide dismutase (SOD) activation and enzyme cofactor activity, making the complex more biologically active than uncomplexed GHK in most published models

The combination of glutathione and vitamin C can enhance their individual effects