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This is a known risk with compounded medications generally, because compounding pharmacies can adjust formulations over time

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People who should avoid semaglutide: Individuals with personal or family history of medullary thyroid carcinoma (MTC) Individuals with MEN-2 (Multiple Endocrine Neoplasia type-2) Those with past pancreatitis Pregnant or breastfeeding individuals Anyone with a known allergy to semaglutide People who typically require special caution: Those with severe gastrointestinal disorders (e.g., gastroparesis) People with serious kidney disease Those taking other GLP-1 medications at the same time Starting Semaglutide Dose for Weight Loss Proper semaglutide dosing for weight management is done gradually to minimize side effects and maximize results

Some small studies and case reports show specific probiotics or brief antibiotic courses reduce TMA and the odor in some people