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Promotes deepest and most restorative stages of rest

Linker instability leads to premature release of toxic payloads and undesired damage to untargeted healthy cells, which can lead to systemic toxicity and adverse effects

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It operates through a dual mechanism, inducing ferroptosis by directly promoting iron oxidation or indirectly inhibiting GPX4 activity [137]

[1] Elongation of telomeres by epitalon was sufficient to surpass the Hayflick limit in a cell culture of human fetal fibroblast cells, extending their proliferative potential from termination at the 34th passage in the control cell population to beyond the 44th passage in the treated cell population, while increasing the lengths of their telomeres to levels comparable to those of cells in the original culture