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Moreover, a TNF promoter polymorphism has been linked with susceptibility to NASH development 22

Published Research on 5-Amino-1MQ Foundational DIO Mouse Study Neelakantan et al., Biochemical Pharmacology (2018) This paper introduced 5-Amino-1MQ as a selective and membrane-permeable small molecule inhibitor of NNMT and tested it in 3T3-L1 adipocytes and in male C57BL/6J mice maintained on a high-fat diet

doi: 10.14218/JCTH.2022.00415 51

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