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Chemical modifications can improve stability, alter pharmacokinetics, or enhance target selectivity, potentially addressing traditional limitations of peptide drugs

Yes, Hepaglide (Semaglutide base) can be used to treat Non-alcoholic Fatty Liver Disease (NAFLD), particularly Noncirrhotic Nonalcoholic Steatohepatitis (NASH) with moderate to advanced liver scarring

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Clinical trial data for retatrutide, including Phase 2 results published in the New England Journal of Medicine (Jastreboff et al., 2023), identified gastrointestinal adverse events as the most common side effects reported by participants

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