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GLP-1R is found in many organs like pancreas, kidney, GI tract and brain, but is highly expressed in pancreas

Lixisenatide (Lyxumia) can be stored for 14 days after first use at temperatures up to 30C

Never opt for injections from an unlicensed source

Among the most promising non-incretin receptor targets are amylin (Amy) receptors (AMYRs), supported by data from phase I and phase II clinical trials showing efficacy of the long-acting amylin and calcitonin receptor agonist, cagrilinitide (Cagri), both as monotherapy 2,3 and in combination with the selective GLP-1R agonist, semaglutide 4,5

However, the GI tract secretes numerous other peptides in response to ingested nutrients that may also play a role in energy and glucose homeostasis