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This complex terminates the flow of electrons through the ETC, reducing oxygen to water
In the mitochondrial pathway, H 2 O 2 increases calcium ion concentrations within the mitochondria [77], regulates Bcl-2 family protein expression and activity, leading to decreased mitochondrial membrane potential, cytochrome c release, and ultimately triggering apoptosis [78]
Journal of lipid research 56, 2237 (2015)
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