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36 Because appetite reduction is common with GLP-1 agonists, and many individuals on GLP-1 therapies are counseled to prioritize protein and/or follow a ketogenic diet to support muscle maintenance during weight loss, fiber intake is often reduced significantly as fruits, vegetables and grains are eliminated
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Through these combined mechanisms, GLP-1 RAs may contribute to remodeling of bile acid pools both directly and indirectly via microbiota interactions, thereby reinforcing gut-liver endocrine crosstalk and metabolic homeostasis (87)
Studies suggest effects on growth factor signaling pathways
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