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Acknowledgements We thank Dr Serge Luquet, Giuseppe Gangarossa, Nicolas Thiebaud and Claire Martin for their advice and helpful discussions
In our initial phenotype-driven screen, 238 semi-cloned embryos were produced from Trim-library-1 and Trim-library-2, among which two embryos exhibited PGC failure, and two others showed reduced PGC numbers (Supplementary information, Fig
Missed Dose Protocol: Administer as soon as remembered within 4 days (96 hours)
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Weight Loss Begins: Many individuals start to see more noticeable weight loss, often around 1-5% of their total body weight by the end of this phase
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