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Combined triad-GSH metabolism model simulations: quinone metabolism and ROS production Following the parameterisation and sensitivity analysis, the triad model was expanded to include GS-H 2 Q adduct formation (quinone removal) and was combined with the glutathione metabolism model constructed by Reed et al

Metabolism & Conjugation: Glutathione conjugation performed a great role in the metabolism of chlorothalonil and subsequent complex metabolic processing of these conjugates occurs in particular renal uptake and urinary excretion of thiol-derived metabolites

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