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Mitochondrial metabolism is a key determinant of this polarization: M1 macrophages rely on glycolysis and have broken TCA cycles (as described), whereas M2 macrophages rely on intact OXPHOS and fatty acid oxidation, with high mitochondrial spare respiratory capacity (45)
Delta (Phospho) Sleep Inducing Peptide induces changes in the circadian locomotor behavior in rats
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Despite sharing a common precursor with GLP-1, GLP-2 has a distinct primary function
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