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Further, once patients achieve their desired weight, therapies that are safer, cheaper, and/or more convenient to administer may be needed to help sustain the durability of the response

In his practice, he hardly ever hears middle-aged and older patients say they want to live longer

Semaglutide# Semaglutide is a selective GLP-1 receptor agonist with no amylin activity

Simple timing framework Baseline Discuss baseline labs before starting or escalating, especially with diabetes, kidney disease, gallbladder history, eating-disorder history, or major calorie restriction

Smoking impairs blood flow to the skin and directly damages collagen through oxidative stress