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B12 is water-soluble, so your body will excrete what it doesn't need
When to discuss a dose increase If you have been at your current dose for four or more weeks with minimal appetite suppression or weight change, a dose increase is usually the appropriate next step
Lee CP, et al
Research on transdermal delivery of herbal extracts for metabolic effects is limited
Step 1: Consult your GP first Your first step should be a conversation with your NHS GP or prescribing clinician to rule out other causes for your symptoms and ensure your thyroid medication (like levothyroxine) dose is appropriate
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