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While Mounjaro has a higher "peak," of both the medications that are well considered to be highly successful

The most common side effects are digestive upset, including nausea constipation

The needle used is very fine, and the injection is administered subcutaneously (just under the skin), not into muscle, which reduces pain

Research supports its various benefits, though individual responses vary based on age, overall health status, and existing dietary patterns

In regulating the response to inflammation of the endothelium, dulaglutide counteracts high glucose-induced activation of the NLR family pyrin domain containing 3 (NLRP3) inflammasome and suppresses maturation and release of IL-1 and IL-18