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This flood of NAD+ in the fat cells forces them to continuously burn energy rather than store it, leading to rapid reductions in fat mass without the need for dietary changes in animal models

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If oral B12 replacement has been trialled in a person with metformin-associated B12 deficiency, I would suggest that a repeat measurement of B12 levels after 812 weeks is a good time to reassess whether absorption is adequate or whether a switch to intramuscular replacement is required

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This direct delivery helps your body's cells get the B12 they need quickly and easily