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P values less than 5% were considered significant, and no adjustment for multiplicity was performed

Several peptides inhibit this process at the enzymatic level

We identified that GLP-1R agonism reduced ethanol consumption, mitigated ethanol-induced upregulation of several liver metabolizing enzymes, including Cyp2e1 and also reduced Cyp2e1 independent of ethanol intake

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10.1038/s41392-020-00428-9 92 YangW